New ICD-10-CM Codes and Guidelines are out, take effect Oct. 1

By Brian Murphy

The new ICD-10-CM codes and Official Guidelines are out. I’ve included relevant links below.

There are 252 new codes, 36 deleted, and 13 revised codes. These take effect October 1, 2024. Here are some interesting additions, from my non-clinical perspective:

Obesity classes added to E66.8 Other obesity. These include the following:

• E66.811 Obesity, class 1
• E66.812 Obesity, class 2
• E66.813 Obesity, class 3
• E66.89 Other obesity not elsewhere classified

Additional specificity for capturing obesity in pediatric patients. E66 Overweight and obesity now instructs the coder to code to identify body mass index, if known, for adults (Z68.1-Z68.45) or pediatrics using Z68.5- (the pediatric addition is new).

“In remission” codes added to a wide range of lymphoma codes including C81 Hodgkin lymphoma, C82 Follicular lymphoma, C83 Non-follicular lymphoma, C84 Mature T/NK-cell lymphomas, C85 Other specified and unspecified types of non-Hodgkin lymphomas, C86 Other specified types of T/NK-cell lymphomas, and C88 Malignant immunoproliferative diseases and certain other B-cell lymphomas.

Additional instruction added to D89.83, Cytokine release syndrome, which reads, “use additional code for adverse effect, if applicable, to identify immune checkpoint inhibitors and immunostimulant drugs (T45.AX5).” Cytokine release syndrome became much more prominent during the COVID outbreak.

Addition of presymptomatic Type 1 diabetes mellitus codes, including E10.A, Type 1 diabetes mellitus, presymptomatic; Unspecified (E10.A0), Stage 1 (E10.A1) and Stage 2 (E10.A2)

Additional instruction added to E11 (Type 2 diabetes mellitus) and E13.6 (Other specified diabetes mellitus with other specified complications) to use an additional code for injectable non-insulin antidiabetic drugs (Z79.85) and additional code for hypoglycemia level, if applicable (E16.A-). E16.A is further stratified with new level 1 (E16.A1), level 2 (E16.A2), and level 3 (E16.A3) codes.

Addition of a huge range of codes related to eating disorders, specified as mild, moderate, severe, extreme, and in remission codes. These include additions to the following code ranges: F50.0 Anorexia nervosa, F50.02 Anorexia nervosa, binge eating/purging type, F50.2 Bulimia nervosa, F50.81 Binge eating disorder, and F50.8, Other eating disorders. Here’s one example:

• F50.010, Anorexia nervosa, restricting type, mild (BMI greater than or equal to 17kg/m2)
• F50.011, Anorexia nervosa, restricting type, moderate (BMI 16.0-16.99 kg/m2)
• F50.012, Anorexia nervosa, restricting type, severe (BMI 15.0-15.99 kg/m2)
• F50.013, Anorexia nervosa, restricting type, extreme (BMI less than 15.0 kg/m2)
• F50.014, Anorexia nervosa, restricting type, in remission (full or partial)
• F50.019, Anorexia nervosa, restricting type, unspecified

New code G90.81, Serotonin syndrome/serotonin toxicity

New code G93.45, Developmental and epileptic encephalopathy

I16.1, Hypertensive emergency, now includes several new “use additional code” instructions

Addition of new detail codes to the I26 Pulmonary embolism series.

New code Z51.A, Encounter for sepsis aftercare

New code Z59.71, Insufficient healthcare coverage, and Z59.72, Insufficient welfare support.

Addition of pediatric BMI codes in the Z68.5 series for greater specificity.

… and many others besides. Too many to list here so I recommend checking the links below. Anything excite you?

Obviously very important to get this specificity in the record. Share these with your coding teams!

For additional reading

New ICD-10-CM codes (and addenda): https://www.cms.gov/medicare/coding-billing/icd-10-codes/2025-icd-10-cm

New ICD-10-CM Official Guidelines for Coding and Reporting: https://www.cms.gov/files/document/fy-2025-icd-10-cm-coding-guidelines.pdf